Mesopotamia definition

mĕsə-pə-tāmē-ə
An ancient region of southwest Asia between the Tigris and Euphrates Rivers in modern-day Iraq. Probably settled before 5000 bc , the area was the home of numerous early civilizations, including Sumer, Akkad, Babylonia, and Assyria. It declined in importance after Mongol invaders destroyed its extensive irrigation system in ad 1258.
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(place, loosely) The entire region between these rivers, extending to the Persian Gulf.
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(place) Ancient country in SW Asia, between the upper Tigris & Euphrates rivers: a part of modern Iraq.
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