While he was engaged upon some pieces for the convent of the Dominican friars, he made the acquaintance of Savonarola, who quickly acquired great influence over him, and Bartolommeo was so affected by his cruel death, that he soon after entered the convent, and for some years gave up his art.
Bartolommeo learned from the younger artist the rules of perspective, in which he was so skilled, while Raphael owes to the frate the improvement in his colouring and handling of drapery, which was noticeable in the works he produced after their meeting.
Fr Bartolommeo's figures had generally been small and draped.
The majority of Bartolommeo's compositions are altar-pieces.
They are remarkable for skill in the massing of light and shade, richness and delicacy of colouring, and for the admirable style in which the drapery of the figures is handled, Bartolommeo having been the first to introduce and use the lay-figure with joints.