From Alexandria we get Athanasius, Didymus and Cyril; from Cyrene, Synesius; from Antioch, Theodore of Mopsuestia, John Chrysostom and Theodoret; from Palestine, Eusebius of Caesarea and Cyril of Jerusalem; from Cappadocia, Basil, Gregory of Nyssa and Gregory of Nazianzus.
He first settled in Egypt, hearing the lectures of Didymus, the Origenistic head of the catechetical school at Alexandria, and also cultivating friendly relations with Macarius the elder and other ascetics in the desert.
In the 4th century Pamphilus, Eusebius of Caesarea, Athanasius, the Cappadocians, Didymus, and Rufinus were on the side of Origen against the attacks of Methodius and many others.
Didymus, writing in the year 60, made the first step towards establishing this pleasant-sounding scale upon a mathematical basis, by the discovery of the lesser tone; but unhappily he placed it in a false position below the greater tone.
Jerome's mind was evidently full of anxiety about his translation of the Old Testament, for we find him in his letters recording the conversations he had with learned men about disputed readings and doubtful renderings; the blind Didymus of Alexandria, whom he heard interpreting Hosea, appears to have been most useful.