He was concerned in the Fronde of 1651, but soon afterwards became reconciled with Mazarin, and in 16J4 married the cardinal's niece, Anne Marie Martinozzi (1639-1672), and secured the government of Guienne.
The duchess of Vendome's grandson, Louis Joseph, inherited Penthievre in 1669, but it was taken from him by decree in 1687 and adjudged to Anne Marie de Bourbon, princess of Conti.
On return to England Anne-Marie was diagnosed with a grade IV brain stem glioma for which there is no cure.
Henrietta's daughter, Anne Marie (1669-1728), became the wife of Victor Amadeus II., duke of Savoy, afterwards king of Sardinia; her son was King Charles Emmanuel III., and her grandson Victor Amadeus III.
