What-s-up-with Definition

(colloquial, rhetorical question) Used to express disbelief or curiosity.

They raised my electricity rates again. What’s up with that?
What’s up with all this new music they’re playing?
Wiktionary
(colloquial, rhetorical question, salutation) Said to express that a person's behavior is out of the ordinary.
What’s up with you?
Wiktionary

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