What-s-up Definition

(idiomatic, colloquial) What are you doing?; what is happening?

Wiktionary

(informal) How are you?; how are you feeling?

Wiktionary
(idiomatic, colloquial) What’s the matter?
Wiktionary

(rhetorical question, colloquial) A casual greeting with a meaning similar to how are you? or nice to meet you.

Wiktionary

Origin of What-s-up

  • Made popular by the cartoon character Bugs Bunny who used it as early as 1940 as part of his catch phrase “What’s up Doc?”.

    From Wiktionary

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