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translocation Definition

trans·lo·ca·tion (trans′lō kā′s̸hən, tranz′-)

noun

  1. an act or instance of translocating
  2. Bot. the transport of organic food materials in solution through tissues from one part of a plant to another
  3. Genetics the transfer of a portion of a chromosome to a new location in the chromosome or into another chromosome

translocation Usage Examples

Preposition: of

  • protein: Nuclear translocation - In every known clock, a key step is the translocation of a protein from the cytoplasm into the nucleus.
  • specie: There are international criteria concerning the translocation of species which had to be satisfied.

Converse of object

  • associate: Promote local byelaws to prevent the use of livebait and associated translocation of fish into vendace waters and their catchments.
  • have: Almost a third of adult patients have a specific chromosome translocation; " Philadelphia Positive " ALL.
  • carry: Ms Tims asks if carrying this balanced translocation means that she is ill?
  • call: Research showed that there had been an exchange of material between chromosomes 9 and 22 - called a translocation.

Adjective modifier

  • chromosomal: Where trisomy 18 is caused by an unbalanced chromosomal translocation, chromosomal analysis should be carried out on both parents.
  • unbalanced: Parental chromosome analysis should be offered where trisomy 13 is due to an unbalanced translocation.
  • macular: Macular translocation for a patient with age-related macular degeneration.
  • reciprocal: I had what was known as a balanced reciprocal translocation, involving chromosomes 8 and 12.
  • balanced: Figure 2 - Array analysis of derivative chromosomes from a balanced translocation.
  • bacterial: Thus patients should be recommended to use such pastes to reduce the risk of bacterial translocation.

Modifies a noun

  • breakpoint: Subsequently, I was awarded an Imperial Cancer Research Trust fellowship to clone the translocation breakpoint causing Ewing's Sarcoma.
  • pathway: Gram negative bacteria have evolved a number of different protein translocation pathways across the outer membrane.
  • project: How many more years will the translocation project run for?
  • attempt: If appropriate, undertake three experimental translocation attempts by 2005.

Noun used with modifier

  • chromosome: Almost a third of adult patients have a specific chromosome translocation; " Philadelphia Positive " ALL.
  • habitat: Habitat translocation a best practice guide is based on the results of an extensive review of habitat translocation projects.
  • protein: Gram negative bacteria have evolved a number of different protein translocation pathways across the outer membrane.
  • proton: For functional studies we reconstitute purified enzyme into liposomes, to analyze coupling between electron transfer and proton translocation.