telomere

Modifies a noun

• shortening: However, telomere shortening cannot be the only mechanism involved in aging at the cellular level.
• length: This new study looked at telomere length in families from northern Belgium.
• maintenance: Telomere maintenance is essential for tumor cells to by-pass replicative senescence and become immortal.
• dysfunction: Recent evidence suggests that defects in DNA maintenance pathways and telomere dysfunction promote genomic instability and drives development of the disease.
• erosion: One of the current models suggests that during the early stages of cancer telomere erosion leads to short dysfunctional telomeres.
• dynamics: Rather, socio-economic status appears to have an impact on telomere dynamics.