On April 7th, 1541, he sailed from Lisbon with Martim Alfonso de Sousa, governor designate of India, and lived amongst the common sailors, ministering to their religious and temporal needs, especially during an outbreak of scurvy.
Martim Affonso de Sousa, having obtained a grant, fitted out a considerable armament and proceeded to explore the country in person.
Pero Lopes de Sousa received the grant of a captaincy, and set sail from Portugal at the same time as his brother, the founder of Sao Vicente.
Sufficient capital was attracted between the year 1531 (in which De Sousa founded the first captaincy) and the year 1548 to render these colonies an object of importance to the mother country.
Thome de Sousa was the first person nominated to the important post of governorgeneral.