Santa RosaSan·ta Ro·sa
- one of the Santa Barbara Islands: 17 mi (27 km) long
- city in W Calif., north of San Francisco
Origin of Santa RosaSp, St. Rose (of Lima) (1586-1617): 1st New World saint
A city of northern California north-northwest of San Francisco. Luther Burbank lived here, and his experimental gardens are preserved as a memorial.