Now Chiefly Dial. to make the sign of the cross over, or to bless, as a protection against evil
Origin of sainMiddle English sainen from Old English segnian from Classical Latin signare, to sign, make the sign of the cross on from signum: see sign
(third-person singular simple present sains, present participle saining, simple past and past participle sained)
Old English seÄ¡nian, from Latin signÅ.