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ribozyme Definition

ribo·zyme (bə zīm′)

noun

a molecule of RNA that acts as an enzyme, used in genetic research and gene therapy

ribozyme Usage Examples

Modifies a noun

  • activity: A second rolling circle event makes a long linear +ve strand which is again cleaved by the ribozyme activity.
  • drug: Angiozyme is likely to be the first ribozyme drug to be approved.
  • therapy: One of the current challenges is the application of ribozyme therapy for dominant mutations coupled with wild-type gene augmentation to overcome haploinsufficiency.

Noun used with modifier

  • hammerhead: The catalytic role for Mg 2+ in the hammerhead ribozyme is assured from the detailed mechanistic studies.
  • virus: Northern blot analysis was consistent with accurate cleavage of the minigenome transcript by the hepatitis { delta } virus ribozyme.