In 83 Tigranes, the king of Armenia, invaded Syria, and by 69 his conquest had reached as far as Ptolemais, when he was obliged to evacuate Syria to defend his own kingdom from the Romans.
The loss of Ptolemais in 1291 stirred the pope to renewed enthusiasm for a crusade.
Xlv., though the unsoundness of the text in certain parts makes it difficult to speak with certainty, would suit the marriage of Alexander Balas at Ptolemais in 150 B.C., at which the high priest Jonathan was present as an honoured guest.
The compatibility of Christian and later Neo-Platonic ideas is evidenced by the writings of Synesius, bishop of Ptolemais, and though Neo-Platonism eventually succumbed to Christianity, it had the effect, through the writings of Clement and Origen, of modifying the tyrannical fanaticism and ultradogmatism of the early Christian writers.
SYNESIUS (c. 373 - c. 414), bishop of Ptolemais in the Libyan Pentapolis after 410, was born of wealthy parents, who claimed descent from Spartan kings, at Cyrene between 370 and 375.