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polypeptide Definition

poly·pep·tide (päl′i peptīd′)

noun

a substance containing two or more amino acids in the molecule joined together by peptide bonds

Etymology: poly- + peptide

polypeptide Usage Examples

Converse of object

  • encode: They have similar amino acid sequences throughout the length of the polypeptide encoded by the open reading frame.
  • form: In the molecule above, the two peptides have joined together to form a dipeptide; many peptides join together to form a polypeptide.
  • associate: Electrophoresis and related enzymatic techniques have identified most of the polypeptides associated with PSII.
  • identify: These systems are biochemically dissected to identify the functionally relevant polypeptides and to study their mechanism of action.
  • secrete: This report documents that islet cell tumors may function by secreting pancreatic polypeptide but not cause symptoms.
  • call: Sequences of amino acids longer than, say, 50, are called polypeptides.

Adjective modifier

  • synthetic: Such experiments have been supported fully by experiments with synthetic polypeptides and, more recently, a synthetic enzyme.
  • pancreatic: In contrast, staining of the tumor for pancreatic polypeptide was strongly positive.
  • single: SDS-PAGE and Western blot analyzes demonstrated that the structural protein of the virus was composed of a single major polypeptide of 63 kD.
  • nascent: Look for the tunnel through which nascent polypeptides emerge.
  • hydrophobic: Hydrophobic polypeptides and proteins play a crucial role in biological processes.
  • large: Serine Protease In the diagram above a small peptide is shown being cleaved, while the usual substrate would be a larger polypeptide.

Modifies a noun

  • chain: Remember a protein is a polypeptide chain: a string of amino acids joined together.
  • backbone: In an a -helix ( alpha helix ), the polypeptide backbone follows a helical path.
  • hormone: The Metabolic Effects of Insulin Insulin is a polypeptide hormone that travels around the bloodstream.
  • sequence: An operon is a tightly packed polypeptide sequence consisting of a control region followed by a group of genes.
  • conformation: For further details, see section 1.6 of the recommendations on polypeptide conformation [ 6 ] or the recommendations on stereochemistry [ 7 ] .
  • structure: We know very accurately: 1. bond lengths in polypeptides, 2. planar groupings in the polypeptide structure.

Noun used with modifier

  • kda: It is initially synthesized as a 76 kDa polypeptide using host cell transcription and translation machinery.
  • tissue: AB - BACKGROUND: Tissue polypeptide specific antigen ( TPS ) recently was introduced as an indicator of cell proliferation in various tumors.