Origin of peyoteAmerican Spanish from Nahuatl peyotl, caterpillar, with reference to the down in the center
- A spineless, dome-shaped cactus (Lophophora williamsii) native to Mexico and the southwest United States, having buttonlike tubercles that contain the hallucinogen mescaline and are traditionally used in rituals by certain Native American peoples. Also called mescal .
- Peyote buttons.
Origin of peyoteAmerican Spanish from Nahuatl peyotl caterpillar cocoon, peyote ( because the tufts of woolly hair in the center of its tubercles resemble caterpillar cocoons )