mutagenesis Hear it!

mutagenesis Definition

mu·ta·gen·esis (myo̵̅o̅t′ə jenə sis)

noun

the occurrence or production of mutation

Etymology: muta(tion) + genesis

mutagenesis Usage Examples

Preposition: of

  • protein: Site-directed mutagenesis of the proteins can be used to identify amino acids that are important in appropriate targeting in health and disease.

Converse of object

  • direct: Site directed mutagenesis has been used to generate such mutants.
  • use: We use site-directed mutagenesis to couple this information to structural features of the proteins.
  • clon: Cloning, mutagenesis and expression The domains were amplified from cDNA using polymerase chain reaction ( PCR ).
  • induce: Our present study clearly demonstrates that anticancer chemotherapy can induce mutagenesis in vivo in various pediatric cancer patients.

Adjective modifier

  • site-directed: We use site-directed mutagenesis to couple this information to structural features of the proteins.
  • insertional: A schematic illustration of insertional mutagenesis with one of our gene trap vectors.
  • random: We are using molecular genetic approaches, in particular random mutagenesis, to analyze fungal genes involved in the disease process.
  • targeted: A ' marker switch ' approach for targeted mutagenesis of genes in Schizosaccharomyces pombe.
  • conventional: For this we are using molecular modeling to investigate docking of the novel compounds, as well as conventional mutagenesis and expression techniques.

Modifies a noun

  • experiment: The structural information is being used to guide rational mutagenesis experiments coupled with biochemical studies to understand better the functioning of the enzyme.
  • screen: This tool provides the basis for an ongoing mutagenesis mosaic screen.
  • study: By coupling this technique to mutagenesis studies, we are able to determine the actual sites of phosphorylation chosen by specific kinases.
  • program: The goal of the mutagenesis programs is the production of mouse models of inherited human disease.
  • strategy: The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
  • datum: The results of the simulation with a flexible ligand are in good agreement with current NMR data and site-directed mutagenesis data.

Noun used with modifier

  • transposon: The mutants were generated by random transposon mutagenesis with the Tn pho A transposon.
  • insertion: The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
  • vitro: The theory and application of in vitro mutagenesis, transgenic animals, and DNA fingerprinting.
  • saturation: Using this technique in combination with another mutagenesis method called saturation mutagenesis the ee value has been improved to more than 90 per cent.

Browse dictionary entries near mutagenesis

  1. mutagen
  2. mutable
  3. mutability
  4. musty
  5. mustn't
  6. musth
  7. muster
  8. musteline
  9. mustee
  10. mustardy
  1. mutant
  2. mutate
  3. mutation
  4. mutatis mutandis
  5. mutative
  6. mutchkin
  7. mute
  8. mute swan
  9. Mutex
  10. muticous