mutagenesis

Preposition: of

• protein: Site-directed mutagenesis of the proteins can be used to identify amino acids that are important in appropriate targeting in health and disease.

Converse of object

• direct: Site directed mutagenesis has been used to generate such mutants.
• use: We use site-directed mutagenesis to couple this information to structural features of the proteins.
• clon: Cloning, mutagenesis and expression The domains were amplified from cDNA using polymerase chain reaction ( PCR ).
• induce: Our present study clearly demonstrates that anticancer chemotherapy can induce mutagenesis in vivo in various pediatric cancer patients.

Adjective modifier

• site-directed: We use site-directed mutagenesis to couple this information to structural features of the proteins.
• insertional: A schematic illustration of insertional mutagenesis with one of our gene trap vectors.
• random: We are using molecular genetic approaches, in particular random mutagenesis, to analyze fungal genes involved in the disease process.
• targeted: A ' marker switch ' approach for targeted mutagenesis of genes in Schizosaccharomyces pombe.
• conventional: For this we are using molecular modeling to investigate docking of the novel compounds, as well as conventional mutagenesis and expression techniques.

Modifies a noun

• experiment: The structural information is being used to guide rational mutagenesis experiments coupled with biochemical studies to understand better the functioning of the enzyme.
• screen: This tool provides the basis for an ongoing mutagenesis mosaic screen.
• study: By coupling this technique to mutagenesis studies, we are able to determine the actual sites of phosphorylation chosen by specific kinases.
• program: The goal of the mutagenesis programs is the production of mouse models of inherited human disease.
• strategy: The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
• datum: The results of the simulation with a flexible ligand are in good agreement with current NMR data and site-directed mutagenesis data.

Noun used with modifier

• transposon: The mutants were generated by random transposon mutagenesis with the Tn pho A transposon.
• insertion: The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
• vitro: The theory and application of in vitro mutagenesis, transgenic animals, and DNA fingerprinting.
• saturation: Using this technique in combination with another mutagenesis method called saturation mutagenesis the ee value has been improved to more than 90 per cent.