In order to reduce the pulse to its normal rate in these cases, without at the same time lessening the power of the heart, the drug must be given in doses of about two minims of the tincture every halfhour and then every hour until the pulse falls to the normal rate.
The British Pharmacopoeia contains (i) an extract of the fresh corm, having doses of 4 to i grain, and (2) the Vinum Colchici, made by treating the dried corm with sherry and given in doses of 10 to 30 minims. This latter is the preparation still most generally used, though the presence of veratrine both in the corm and the seeds renders the use of colchicine itself theoretically preferable.
They contain a volatile oil which does not occur in the corm, and their proportion of colchicine is higher, for which reason the Tinctura Colchici Seminum- dose 5 to 15 minims - is preferable to the wine prepared from the corm.
The pupils at Brienne, far from receiving a military education, were grounded in ordinary subjects, and in no very efficient manner, by brethren of the order, or society, of Minims. The moral tone of the school was low; and Napoleon afterwards spoke with contempt of the training of the "monks" and the manner of life of the scholars.
Ten to twenty minims of ether, subcutaneously injected, constitute perhaps the most rapid and powerful cardiac stimulant known, and are often employed for this purpose in cases of syncope under anaesthesia.