Joffroy's sign

Joffroy's sign definition - medical

Jof·froy's sign (zhô-frwäzˈ)

noun
  1. An indication of exophthalmic goiter in which the facial muscles remain immobile when the eyeballs are rolled upward.
  2. An indication of the early stages of brain disease in which an individual is unable to mentally compute simple mathematical calculations.

The American Heritage® Medical Dictionary Copyright © 2009 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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