- frank; honest; candid; sincere: a man-to-man talk
- designating or of a type of defense used in various team sports, in which each defensive player guards a specified offensive player
See man-to-man in American Heritage Dictionary 4
- Marked by forthrightness and honesty: had a man-to-man talk about the facts of life.
- Sports Of, relating to, or being a system of defense in which a defensive player guards a specific offensive player.
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