A much frequented route into Phrygia and the Maeander valley began at.
The district comprised three extremely fertile valleys formed by the outflow of three rivers, among the most considerable in Asia Minor: the Hermus in the north, flowing into the Gulf of Smyrna, though at some distance from the city of that name; the Cayster, which flowed under the walls of Ephesus; and the Maeander, which in ancient times discharged its waters into the deep gulf that once bathed the walls of Miletus, but which has been gradually filled up by this river's deposits.
The great names of this school are Theodorus and Rhoecus of Samos; Bathycles of Magnesia on the Maeander; Glaucus,.
After the Persian conquest the Maeander was regarded as its southern boundary, and in the Roman period it comprised the country between Mysia and Caria on the one side and Phrygia and the Aegean on the other.
West of the acropolis were the palace of Xerxes and the Agora, in or near which is the cavern whence the Marsyas, one of the sources of the Maeander, issues.