city in E Tenn., on the Tennessee River: pop. 174,000
Origin:
after Gen. Henry Knox (1750-1806), 1st secretary of war
See Knoxville in American Heritage Dictionary 4
A city of eastern Tennessee on the Tennessee River northeast of Chattanooga. Settled c. 1785, it twice served as the state capital (1796-1812 and 1817-1819). Population: 182,000.