- an ignorant person; ignoramus
- Rare an agnostic
- a member of a secret political party in the U.S. in the 1850s with a program of keeping out of public office anyone not a native-born American: so called because members professed ignorance of the party's activities
- A totally ignorant person; an ignoramus.
- An anti-intellectual.
- An agnostic.
- Know-Nothing A member of a political party in the United States during the 1850s that was antagonistic toward recent immigrants and Roman Catholics.
Party members claimed to know nothing about the party when questioned.