lose one's mind

lose one's mind idiom
Also, lose one's reason. Go crazy, lose one's sanity, as in I thought she'd lost her mind when she said she was going ice-fishing, or That assignment is enough to make me lose my reason. The first expression dates from the late 1500s; the second employs reason in the sense of “unimpaired mental faculties,” a usage dating from the late 1300s. Also see under go out of one's mind; have all one's buttons.

The American Heritage® Dictionary of Idioms by Christine Ammer. Copyright © 2003, 1997 by The Christine Ammer 1992 Trust. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

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