an enzyme that inactivates hyaluronic acid by breaking down its polymeric structure, thus promoting the diffusion of substances through tissues: found in sperm cells, certain venoms and bacteria, etc.
See hyaluronidase in American Heritage Dictionary 4
(hīˌə-lo͝o-rŏnˈĭ-dāsˌ, -dāzˌ)
noun
An enzyme that catalyzes the breakdown of hyaluronic acid in the body, thereby increasing tissue permeability to fluids. Also called spreading factor.