Frataxin Definition

Frataxin Sentence Examples

• The gene for FA codes for a protein called frataxin.

• Normal frataxin is found in the cellular energy structures known as mitochondria, where it is thought to be involved in regulating the transport of iron.

• In FA, the frataxin gene on chromosome 9 is expanded when a particular sequence of bases in the DNA is repeated too many times.

• Ordinarily, there are seven to 22 repeats of the frataxin gene; in FA, this sequence may be repeated between 800 to 1,000 times.

• This extra DNA interferes with normal production of frataxin, thereby impairing iron transport.