They possessed in Cyprus a kingdom, in which they had vindicated for themselves a stronger hold over their feudatories than the kings of Jerusalem had ever enjoyed, and in which trading centres like Famagusta flourished vigorously; and they used the resources of their kingdom, in conjunction with the Hospitallers of Rhodes, to check the progress of the Mahommedans.
They reaped no fruits from the victory, and Cyprus was taken from her after the heroic defence of Famagusta by Bragadino, who was flayed alive, and his skin, stuffed with straw, borne in triumph to Constantinople.
Till 1489 the kingdom of Cyprus survived as an independent monarchy, and its capital, Famagusta, was an important centre of trade after the loss of the coast-towns in the kingdom of Jerusalem.
On the one hand they led to the establishment of emporia in the East - for instance, Acre, and after the fall of Acre Famagusta, both in their day great centres of Levantine trade.
Expeditions against the Yemen and Cyprus were successful, but the loss of Cyprus, accompanied as it was by the barbarous murder of the Venetian commander, Marco Antonio Bragadino, by the seraskier pasha Mustafa's orders, in violation of the terms of the capitulation of Famagusta (August 1571), roused the bitter resentment of the Venetians, previously incensed by Turkish raids on Crete.