Preposition: of

• economy: The unprecedented rise of competition between the monopolies is leading to the ruination of the economy at home.

Converse of object

• bring: He was greatly feared, because he could bring ruination upon anyone for the smallest slight to his honor.

• cause: Is there no end to these people that will cause the ruination of the human race given half a chance?

Adjective modifier

• economic: Watch out for the economic ruination of Spain, I wonder how Max will explain that, with yet more Socialist cut and pastes?