Modifies a noun

• activity: A second rolling circle event makes a long linear +ve strand which is again cleaved by the ribozyme activity.

• drug: Angiozyme is likely to be the first ribozyme drug to be approved.

• therapy: One of the current challenges is the application of ribozyme therapy for dominant mutations coupled with wild-type gene augmentation to overcome haploinsufficiency.

Noun used with modifier

• hammerhead: The catalytic role for Mg 2+ in the hammerhead ribozyme is assured from the detailed mechanistic studies.

• virus: Northern blot analysis was consistent with accurate cleavage of the minigenome transcript by the hepatitis { delta } virus ribozyme.