Although some attain their full development in the body of a single host - in this respect differing from all other Entozoa - the majority do not become sexually mature until after their transference from an "intermediate" to a "definitive" host.
He defined them as possessing radial instead of bilateral symmetry, and as apparently destitute of nervous system and sense organs, as having the circulatory system rudimentary or absent, and the respiratory organs on or coextensive with the surface of the body; he included under this title and definition five classes, - Echinodermata, Acalepha, Entozoa, Polypi and Infusoria.
Milne-Edwards removed the Polyzoa; the group was soon further thinned by the exclusion of the Protozoa on the one hand and the Entozoa on the other; while in 1848 Leuckart and Frey clearly distinguished the Coelenterata from the Echinodermata as a separate sub-kingdom, thus condemning the usage by which the term still continued to be applied to these two groups at least.
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