Sentence Examples


  • The drug is contra-indicated in all cases where the heart is already beating too slowly; in aortic incompetence - where the prolongation of diastole increases the amount of the blood that regurgitates through the incompetent valve; in chronic Bright's disease and in fatty degeneration of the heart - since nothing can cause fat to become contractile.
  • The systole is not altered in length, but the diastole is very much prolonged, and since this is the period not only of cardiac rest but also of cardiac "feeding" - the coronary vessels being compressed and occluded during systole - the result is greatly to benefit the nutrition of the cardiac muscle.
  • The individual muscle-fibres contract and expand more perfectly, and thus the diastole and systole of the heart are rendered more complete, the pulse is slowed, and the blood-pressure is raised.
  • Later in its action, the drug depresses the intra-cardiac motor ganglia, causing prolongation of diastole and finally arrest of the heart in dilatation.
 
 

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