The deleterious influence of high bloodpressure has engaged the attention of physicians and pathologists in later years, and the conclusion arrived at is, that although it may arise from accidental causes, such as malcomposition of the blood, yet that in many instances it is a hereditary or family defect, and is bound up with the tendency to gout and cirrhotic degeneration of the kidney.
Gull and Sutton asserted that in particular states of body, and more especially in the condition associated with cirrhotic kidney, such a fibrosis becomes general, running, as they alleged it does, along the adventitia of arteries and spreading to their capillaries.
They held that the cirrhotic kidney is simply a local manifestation of a general fibrous disease.
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