capital & chief town of French Guiana, on the Atlantic: pop. 42,000
See Cayenne in American Heritage Dictionary 4
(kī-ĕnˈ, kā-)
The capital of French Guiana, on Cayenne Island at the mouth of the Cayenne River. Founded by the French in 1643, it was the center of a penal colony from the 1850s until the 1940s. Population: 61,600.