The definition of cafard is apathy or severe depression.
(noun)An example of cafard is how someone feels who might be prescribed the drug Zoloft.
See cafard in Webster's New World College Dictionary
noun
Origin: Fr, low spirits, cockroach, orig., hypocrite, altered (with pejorative -ard) < MFr caphars < Ar kāfir, hypocrite, lit., infidel: see Kaffir