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bilirubin Definition

bili·ru·bin (bil′i ro̵̅o̅′bin)

noun

the yellowish-red chief pigment, CHNO, of human bile, derived from biliverdin and found in small quantities in blood and urine: high concentrations change the color of blood and urine and result in jaundice

Etymology: ModL < L bilis, bile + ruber, red + -in

bilirubin Usage Examples

Converse of object

  • raise: Ten days post-transfusion she developed cramps, a raised bilirubin, falling Hb and a positive DAT ( IgG ).
  • call: Jaundice is caused by too much of a yellow substance called bilirubin building up in the body.
  • increase: Thirty patients at moderate risk of CBD stones ( moderately increased bilirubin, normal CBD ) underwent IOC.
  • contain: The jaundice is deep with itchy skin, pale stools and dark urine containing bilirubin but no urobilinogen.
  • remove: Jaundice is common in newborns as the liver is not sufficiently developed to efficiently remove bilirubin.
  • change: Normal lab values and when to change Total bilirubin ( normal range ) 3 -- 17 mmol/l.

Preposition: in

  • blood: Therefore, any failure of the bilirubin removal pathway will lead to a build-up of bilirubin in the blood.
  • urine: In these situations, the amount of bilirubin in the urine will rise and give the urine a more yellowish color.

Adjective modifier

  • conjugated: As conjugated bilirubin is water-soluble it will be excreted in the urine which becomes dark.
  • increased: In these situations the hepatocellular function is normal but overwhelmed and so the increased bilirubin is for the most part unconjugated.
  • total: Elevation of total bilirubin was more significantly suppressed in the PG group than in the control group.
  • elevated: Baseline elevations of several liver function tests ( especially elevated bilirubin ) should preclude the use of riluzole ( see section 4.8 ).
  • excess: Hepatocellular function is normal ( although it may deteriorate in prolonged obstruction ) so the excess plasma bilirubin is chiefly conjugated.
  • changed: When this occurs, the changed bilirubin appears in the urine and turns the urine brown.

Modifies a noun

  • level: His bilirubin level had only risen by 5 in the previous 10.5 hours.
  • concentration: Phototherapy remains an effective therapeutic intervention for decreasing bilirubin concentrations.
  • elevation: No differences in frequency of bilirubin elevations were observed between these patients and those without viral hepatitis.
  • test: At 14.25 hours the serum bilirubin test showed raised bilirubin and it was decided to give phototherapy, which was commenced at 16.00 hours.

Noun used with modifier

  • serum: All the liver tests should be normal apart from the serum bilirubin, which is increased.
  • and/or: Transient moderate elevations of ASAT, ALAT and alkaline phosphatases and/or bilirubin have been reported.